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Wild lettuce is a natural remedy sourced from the Lactuca virosa plant. Extracts of the plant’s sap, seeds, and leaves are typically used in wild lettuce products. Touted as a natural treatment for a wide range of health problems, wild lettuce is said to lower stress and relieve pain.


Certain compounds found in wild lettuce appear to have pain-relieving and sedative effects, according to preliminary research conducted on animals.

A study published in the Journal of Ethnopharmacology in 2006 found that lactucin and lactucopicrin—chemicals naturally present in wild lettuce—reduced pain and promoted sedation